VisiCalc was the first spreadsheet program. Originally written for the Apple II it was ported to numerous other platforms. VisiCorp couldn't keep up the momentum of VisiCalc, and others filled the void.
It will run under a variety of Apple II emulators, but... Windows XP and Vista maintain the ability to run 8086 MS-DOS binaries on the 32 bit x86 platform, at least, so you can run the DOS version directly. You can get an executable here from the original creator!